The DoseGrade Blog
Deep dives into supplement science. Every claim backed by real clinical studies, not marketing hype.
How to Pick a Quality Fish Oil: What Actually Matters
Most labels tell you '1,000 mg fish oil' — which is almost meaningless. Here's what actually matters: oxidation, EPA+DHA, form, certification, and storage.
Vitamin D3 and K2: Why They Work Better Together (And How Much K2 You Actually Need)
Vitamin D increases calcium absorption. K2 helps direct calcium where it belongs. Here's the mechanism, evidence, dosing, and the one critical drug interaction.
When to Take Creatine: What the Research Actually Says
Loading phase or no loading? Before or after a workout? Monohydrate or HCl? Here's what the research actually shows — and what doesn't matter.
Best Magnesium for Sleep: Glycinate vs Threonate vs Oxide (2026)
Not all magnesium is created equal. We break down the clinical evidence for glycinate, threonate, and oxide to help you pick the right form for better sleep.
Ashwagandha: Evidence-Based Dosage, Benefits, and Side Effects
Ashwagandha is one of the most studied adaptogens available. Here's what the clinical trials actually show about dosage, benefits, and risks.
5-HTP and SSRIs: Why This Combination is Dangerous
5-HTP seems harmless — it's just a natural serotonin precursor. But combining it with antidepressants can trigger serotonin syndrome, a medical emergency. Here's why.
The Beginner's Evidence-Based Supplement Stack (2026)
Most supplement stacks are overcomplicated. Here are the 5 foundational supplements that actually have strong evidence — and how to take them properly.
NMN vs NR: Which NAD+ Precursor Has Better Evidence?
NAD+ declines with age, and both NMN and NR promise to restore it. But the clinical evidence for each tells very different stories.