Ginger

Also known as: Zingiber officinale, ginger root, gingerol

Grade A — Strong Evidenceherbgutanti-inflammatory
1–2 gWith meals for digestive benefits; 30-60 min before travel for nausea prevention.

Ginger (Zingiber officinale) contains bioactive gingerols and shogaols that inhibit COX and lipoxygenase pathways, providing anti-inflammatory and anti-nausea effects. It has strong evidence as an antiemetic — comparable to dimenhydrinate for motion sickness and effective for pregnancy-related nausea. Meta-analyses also show benefits for reducing muscle soreness (DOMS), osteoarthritis pain, and fasting blood glucose levels.

TL;DR: Excellent evidence for anti-nausea effects (pregnancy, chemotherapy, post-op). Also anti-inflammatory with COX-2 inhibition.

🦠Gut Health🛡️Immunity
Last reviewed: 2026-03-12

Quick Facts

Evidence

Grade A

Studies

3

Interactions

2

Forms

1

Evidence Rating: Grade A — Strong Evidence

Multiple high-quality RCTs, systematic reviews, or meta-analyses with consistent findings.

Interaction Warnings

Warfarin / anticoagulantsModerate

Mild antiplatelet activity at high doses (>4g/day); monitor INR

Antidiabetic drugsLow

Modest glucose-lowering effect; may potentiate medication

Important Notes

  • Safe at 1g/day in pregnancy for nausea
  • Stop 2 weeks before surgery at high doses
  • Caution in gallstone disease (stimulates bile)

Clinical Evidence (3 studies)

Ginger for first-trimester nausea and vomiting

Vutyavanich T et al. (2001) — Obstet Gynecol

1g/day significantly reduced nausea and vomiting vs placebo; RCT

View on PubMed

Ginger in gastrointestinal disorders

Haniadka R et al. (2013) — Food Funct

Review of human clinical trials for GI disorders

View on PubMed

Ginger and chemotherapy-induced nausea

Marx W et al. (2017) — Crit Rev Food Sci Nutr

Systematic review and meta-analysis: effective adjunct for CINV

View on PubMed

Alternatives to Consider

These supplements target similar goals and may be worth considering alongside or instead of Ginger.

Probiotics

Grade B

Beneficial bacteria for gut health. Strain selection matters — L. rhamnosus GG, B. infantis 35624, and S. boulardii are best-studied.

🦠 Gut Health🛡️ Immunity

Glutamine

Grade B

Conditionally essential amino acid that is the primary fuel for gut lining cells. RCT evidence for IBS and leaky gut.

🦠 Gut Health🛡️ Immunity

Black Seed Oil

Grade B

Widely studied traditional remedy with strong anti-inflammatory properties from thymoquinone. Evidence for metabolic health, immune modulation, and gut health. Oil form preferred for absorption.

🛡️ Immunity🦠 Gut Health

Related Supplements

Probiotics

Grade B — Moderate Evidence

Beneficial bacteria for gut health. Strain selection matters — L. rhamnosus GG, B. infantis 35624, and S. boulardii are best-studied.

Glutamine

Grade B — Moderate Evidence

Conditionally essential amino acid that is the primary fuel for gut lining cells. RCT evidence for IBS and leaky gut.

Black Seed Oil

Grade B — Moderate Evidence

Widely studied traditional remedy with strong anti-inflammatory properties from thymoquinone. Evidence for metabolic health, immune modulation, and gut health. Oil form preferred for absorption.

Bromelain

Grade B — Moderate Evidence

Proteolytic enzyme from pineapple with evidence for reducing inflammation, swelling, and pain. Comparable to NSAIDs in some studies. Must take on empty stomach for systemic effects.

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⚕️ Important Disclaimer

This information is for educational purposes only. It is not medical advice. Always consult a healthcare provider before starting any supplement regimen, especially if you take medications or have health conditions.

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