Tongkat Ali (Fadogia Blend)

Also known as: fadogia agrestis, longjack + fadogia

Grade C — Preliminarybotanicalhormoneperformance
400–600 mg fadogiaMorning with food; cycle 4 weeks on / 1 week off

Popular testosterone-support herb with rising interest but LIMITED human evidence. Animal studies show testosterone increase but also dose-dependent toxicity. Conservative dosing with cycling strongly advised. Tongkat Ali has far more human data.

💪Muscle & Recovery⚡Energy😊Mood
Last reviewed: 2026-03-12

Quick Facts

Evidence

Grade C

Studies

1

Interactions

1

Forms

1

Evidence Rating: Grade C — Preliminary

Limited human trials, mostly animal or in-vitro data. Promising but not yet proven in robust human studies.

Cycling Protocol

4 weeks on/1 weeks off

Limited safety data; cycling reduces potential for receptor desensitization and testicular stress

Interaction Warnings

Testosterone therapyModerate

May have additive effects with exogenous testosterone — monitor levels.

Important Notes

  • Animal studies only — no published human clinical trials on fadogia agrestis as of 2026
  • High doses showed testicular toxicity in animal models — conservative dosing essential
  • Often combined with Tongkat Ali (which has much more human research)
  • Cycling is strongly recommended due to limited long-term safety data
  • Quality and purity vary widely — third-party testing critical

Clinical Evidence (1 study)

Fadogia agrestis stem extract and testosterone in rats

Yakubu MT et al. (2005) — Asia J Androl

Fadogia agrestis increased testosterone levels dose-dependently; high doses raised testicular cholesterol suggesting steroidogenic stimulus

View on PubMed

Alternatives to Consider

These supplements target similar goals and may be worth considering alongside or instead of Tongkat Ali (Fadogia Blend).

Maca Root

Grade B

Peruvian adaptogen with evidence for libido, mood, and energy. Does not directly affect hormones but may modulate endocrine function. Black and red varieties have different benefit profiles.

⚡ Energy😊 Mood💪 Muscle & Recovery

Creatine Monohydrate

Grade A

One of the most researched supplements in history. Strong evidence for strength, power, and emerging evidence for brain function.

💪 Muscle & Recovery⚡ Energy

Beta-Alanine

Grade A

Increases muscle carnosine levels, buffering acid during high-intensity exercise. Well-supported for 1-4 min high-intensity efforts.

💪 Muscle & Recovery⚡ Energy

Related Supplements

Maca Root

Grade B — Moderate Evidence

Peruvian adaptogen with evidence for libido, mood, and energy. Does not directly affect hormones but may modulate endocrine function. Black and red varieties have different benefit profiles.

Ashwagandha

Grade A — Strong Evidence

Ayurvedic adaptogen with strong clinical evidence for cortisol reduction (15-30%), stress relief, and exercise performance.

Tongkat Ali

Grade C — Preliminary

Southeast Asian herb with emerging evidence for cortisol reduction and hormonal support.

Creatine Monohydrate

Grade A — Strong Evidence

One of the most researched supplements in history. Strong evidence for strength, power, and emerging evidence for brain function.

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⚕️ Important Disclaimer

This information is for educational purposes only. It is not medical advice. Always consult a healthcare provider before starting any supplement regimen, especially if you take medications or have health conditions.

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