Olive Leaf Extract

Also known as: olea europaea, oleuropein, olive leaf

Grade C — Preliminaryherbalcardiovascularimmune
5001000 mgStandardized to 15-20% oleuropein; with or without food

Extract from olive tree leaves rich in oleuropein with evidence for blood pressure reduction, antimicrobial activity, and antioxidant effects. Aligns with Mediterranean diet research. May lower blood pressure comparably to some medications. Monitor if on BP meds.

Last reviewed: 2026-03-12

Quick Facts

Evidence

Grade C

Studies

1

Interactions

2

Forms

1

Evidence Rating: Grade C — Preliminary

Limited human trials, mostly animal or in-vitro data. Promising but not yet proven in robust human studies.

Interaction Warnings

Blood pressure medicationsModerate

Additive hypotensive effects — may cause blood pressure to drop too low.

Diabetes medicationsLow

May lower blood sugar mildly — monitor glucose.

Important Notes

  • Active compound oleuropein has antioxidant, anti-inflammatory, and antimicrobial properties
  • May cause Herxheimer-like reactions (die-off symptoms) when starting
  • Standardization to oleuropein content is important for consistent dosing
  • Part of the Mediterranean diet health halo — extract concentrates beneficial compounds

Clinical Evidence (1 study)

Olive leaf extract and its main component oleuropein on blood pressure: a systematic review and meta-analysis

Lockyer S et al. (2017) — Eur J Nutr

Olive leaf extract significantly reduced systolic and diastolic blood pressure, with effects comparable to captopril in one trial

View on PubMed

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⚕️ Important Disclaimer

This information is for educational purposes only. It is not medical advice. Always consult a healthcare provider before starting any supplement regimen, especially if you take medications or have health conditions.

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